Stanozolol oral intake in the form initially absorbed in the digestive tract, and later transferred to the liver, the presumption is that the blood stream reaches the much less active substance than the injectable form. Studies have shown that oral administration of stanozolol is metabolized in the body two times, where there's injectable only once, so the effects of injection Winstrolu are much higher, especially in terms of increasing protein synthesis.
Another interesting fact is that oral administration of stanozolol, at a dose mg / kg body weight decreases SHBG by 50%. What course reinforces anabolic effect cures. But the point is that the injectable stanozolol SHBG decreases at the same dose of only 11%.
Much of the free TST is bound to SHBG, thus reducing the anabolic effect of TST, thanks stanozolol you can reduce SHBG, thus ensuring better efficiency of the TST. It is therefore recommended after 5 weeks of treatment taking stanozolol in cure because it increases anablic effect.
The synthesis of Stanozolol was first described in 1956 and signed shortly afterwards by Winthrop Laboratories patent. Three years later the first Stanozolol containing medicines have been available under the global brand name Winstrol. As indicated back then were increase in appetite, tissue structure, and treatment of osteoporosis, reduced growth in young people and the improvement of the general condition in the elderly. The indications were however were revised over time, so that today only the treatment of osteoporosis and growth retardation is left over